Innovative science

Technology

Artificial intelligence platform

Introduction

Features

Independently developed artificial intelligence platform is an optimized technology in genomic data analysis and biomarker development. It leverages big data (public data, medical records, experimental data etc.) from data mining, and machine learning technology.
The innovative platform technology enables precision medicine based on the integration of statistics, machine learning and mechanism investigation.
Peer reviewed articles, patents and commercialization are testament to superiority performance of platform technology and CbsBioscience’s commitment to innovation.
1. CBS STATS : 20 modules and 149 algorisms optimized by combo-gene statistical analysis
2. CBS MLBS : Secure multi-center validation success rate over 95% via machine learning for cross validation
3. CBS PINGS : Mechanism investigation based analysis provides scientific evidence for precision medicine service and drug development

CBS STATS (Combo-gene statistical analysis system)

Big data-based, Al-driven, Precision Medicine Company


CBS MLBS

Conventional biomarker development process and example of validation (without CBS MLBS)

Training Set
AUC Sensitivity (%) Specificity (%) Accuracy (%) PPV (%) NPV (%)
0.962 88.89 96.97 93.33 96.00 91.43
Validation Set
AUC Sensitivity (%) Specificity (%) Accuracy (%) PPV (%) NPV (%)
0.694 87.10 23.53 64.58 67.50 50.00

CbsBio biomarker development process and example of validation (with CBS MLBS)

Training Set
AUC Sensitivity (%) Specificity (%) Accuracy (%) PPV (%) NPV (%)
0.869 81.48 84.85 83.33 81.48 84.85
Validation set
AUC Sensitivity (%) Specificity (%) Accuracy (%) PPV (%) NPV (%)
0.842 82.26 79.41 81.25 87.93 71.05

CBS PINGS

PPI analysis

Disease related proteins(Disease Pathway)
Protein protein interaction analysis

  • Protein interacts with one or multiple proteins in physical or functionally
  • Enables quantitative analysis based on protein interaction frequency

Signal pathway analysis

Interacting gene analysis

Disease related genes(Disease Pathway)
Gene gene interaction analysis

  • Gene interacts with one or multiple proteins in physical or functionally
  • Enables quantitative analysis based on gene interaction frequency

Treatment benefit prediction score

Drug matching

No. Druggable Gene Druggable Pathway Recommended Drugs
1 AR Pathways in cancer etc. Acetylcysteine
2 HGF Human papillomavirus infection etc. Afatinib
3 HHIP Pathways in cancer etc. Nedocromil

Precision medicine suggestion